The commission that oversees US presidential debates says it will change the format to ensure the remaining two encounters between Donald Trump and Joe Biden are more orderly.
One new measure could be to cut the microphones if the candidates try to interrupt each other, US media report.
The announcement follows Tuesday's ill-tempered debate that descended into squabbling, bickering and insults.
Trump's team has already criticised the commission's plans.
The tone and tactics of the first presidential debate were criticised across the US and around the world.
The fallout, however, has also been dominated by Trump's refusal in the debate to explicitly condemn a far-right group called the Proud Boys.
What are the plans for the next debates?
In Tuesday's debate, the candidates were given two minutes to answer moderator questions, before being allowed to address each other's response.
However, Trump constantly interrupted Democratic candidate Joe Biden leading to a series of chaotic exchanges in which both men talked over each other.
The Commission on Presidential Debates (CPD) - a nonpartisan body that has organised presidential debates since 1988 - said it would soon announce new measures to help moderators "maintain order" in the remaining two debates.
It said the first debate had "made clear that additional structure should be added to the format of the remaining debates to ensure a more orderly discussion of the issues".
CBS News, citing an informed source, said the commission would spend the next 48 hours drawing up new guidelines and rules for the second debate on 15 October in Miami, Florida.
Controlling the candidates' microphones is at the top of the list, CBS said, in order to prevent them interrupting the moderator or each other.
Both campaign teams will be informed of the rules but they will not be subject to negotiation, the source added.
What's the reaction?
Trump campaign communications director Tim Murtaugh, who had described Tuesday's night's chaotic scenes as a "free exchange of ideas", criticised the plans.
"They are only doing this because their guy got pummelled last night," he said.
"President Trump was the dominant force and now Joe Biden is trying to work the refs. They shouldn't be moving the goalposts and changing the rules in the middle of the game."
Kate Bedingfield, deputy manager for Biden's campaign, said the former vice-president would participate "under whatever set of rules the commission develops to try to contain Donald Trump's behaviour".
While one snap poll on the debate gave Biden a slight edge, other opinion polls suggest 90 percent of Americans have already made up their mind how to vote for and the debate may well have made little difference.
In his first interview since the debate, moderator Chris Wallace told the New York Times it was "a terrible missed opportunity" and that he "never dreamed it would go off the tracks the way it did".
The Fox news anchor has come under criticism for struggling to control the debate. However, the CPD on Wednesday praised his "professionalism and skill".
What's the row about Proud Boys?
During the debate, Wallace asked whether the president would condemn white supremacists and tell them to stand down during protests.
When Trump asked who it was he was being told to condemn, Biden twice said "Proud Boys", referring to a far-right, anti-immigrant, all-male group with a history of violence against left-wing opponents.
The president said: "Proud Boys - stand back and stand by. But I'll tell you what... somebody's got to do something about antifa [anti-fascist activists] and the left because this is not a right-wing problem."
Proud Boys members called his "stand by" remark "historic" and an endorsement.
Biden said Trump had "refused to disavow white supremacists".
On Wednesday, Trump appeared to try to walk back on his comments.
At a news conference on the White House lawn a reporter asked him about Proud Boys and he said: "I don't know who they are. I can only say they have to stand down and let law enforcement do their work."
He did not clarify his use of "stand by" in the debate. When asked whether he welcomed white supremacist support he said only that he wanted "law and order to be a very important part of our campaign".
Biden returned to the issue in a tweet on Wednesday, saying: "There's no other way to put it: the President of the United States refused to disavow white supremacists on the debate stage last night."
In his tweet he quoted a comment, addressed to the president, from a Proud Boys online forum that read: "This makes me so happy. We're ready! Standing by sir."