Iraq says its air force has killed eight senior figures from Islamic State, but the group's reclusive leader Abu Bakr al-Baghdadi did not appear to be among the dead.
The air strike hit a meeting of the Islamic State members in a town in western Iraq in Anbar province, near the Syrian border, and also struck a convoy that was carrying Baghdadi to attend it.
The Iraqi air force said in a statement it had "bombed the convoy of the terrorist Abu Bakr al-Baghdadi while he was heading to Karabla to attend a meeting" with Daesh (IS) commanders".
Baghdadi was "transported in a vehicle" after the air strike but "his health status is unknown," the statement said.
Daesh is the Arabic acronym for Islamic State, also known as ISIS or ISIL. Karabla is a town in Iraq's Anbar province near the Syrian border, an Islamic State stronghold, not to be confused with Kerbala, a Shi'ite holy city in the south.
The Iraqi military's announcement was the latest unconfirmed report of the possible death or injury of Baghdadi, who has survived a year of US-led air strikes and multi-sided wars in two countries since proclaiming himself caliph of all Muslims after his forces swept through most of northern Iraq last year.
A Twitter site which publishes statements from Islamic State said "rumours" that an air strike had targeted Baghdadi were false.
A US military official in Baghdad, speaking on condition of anonymity, said the United States has not seen any indications Baghdadi was killed or injured during the operation.
"The location of the meeting was also bombed and many of the group's leaders were killed and wounded. The fate of murderer al-Baghdadi is unknown and he was carried away by a vehicle. His health condition is still unclear," the military said.
Hospital sources and residents said airstrikes hit two houses and killed eight senior local leaders of an Islamic State police force in the town.
Islamic State supporters said on Twitter that even if Baghdadi had been killed, his self-proclaimed caliphate straddling large areas of Iraq and Syria would survive.
"Do you think we would leave the State of the caliphate and abandon it, oh vile world?," asked one of his followers. "This is the religion of God, it rose on the skulls of heroes and martyrs and every time one of them is martyred we rise."
Baghdadi has galvanised militants from around the world, encouraged by his military successes and plans to redraw the map of the Middle East to create a self-sustaining caliphate.
His successes prompted the United States to re-engage in Iraq with air strikes against his fighters three years after pulling out following a long, costly occupation.
Russia, which has launched a bombing campaign to aid its Syrian ally Bashar al-Assad, says its main enemy is Islamic State as well.
An Islamic State fighter reached by telephone could not confirm whether Baghdadi had been in a convoy that was struck, but said the group would fight on whatever his fate: "Even if he was martyred then it will not affect Islamic State. We will lose a leader but there are a thousand Baghdadis."