Manager Sir Alex Ferguson says Manchester United striker Wayne Rooney and defender Nemanja Vidic should be fit for the Premier League football leaders' trip to Tottenham Hotspur on Monday.
Rooney has been sidelined since injuring his ankle against West Bromwich Albion on New Year's Day, while captain Vidic was rested in last week's 1-nil win over Liverpool in the FA Cup.
Goalkeeper Edwin Van der Sar has been suffering from flu for the past two weeks and if he has not sufficiently recovered Tomasz Kusczak is likely to continue to deputise.
The trip to White Hart Lane is widely seen as unbeaten United's biggest challenge so far this season.
Fourth-placed Spurs are eight points behind the leaders.
Tottenham midfield star Gareth Bale is fit after suffering a back spasm that forced him off in their defeat at Everton while central defender Younes Kaboul returns from suspension.