Manchester City have continued their impressive scoring spree to rout Burnley 5-0 in the English FA Cup fourth round and made it 30 goals and seven straight wins in three separate competitions since the turn of the year.
Second-tier Millwall stunned Everton while another English Premier League side, Wolverhampon Wanderers required a 93rd-minute equaliser from Matt Doherty to draw 2-2 with League One Shrewsbury Town.
Newport County, from League Two scored in stoppage time against Championship side Middlesbrough to clinch a 1-1 draw that means a replay.
There was, though, never much chance of a shock at the Etihad from the moment Gabriel Jesus put City ahead with a fine strike after 23 minutes.
Bernardo Silva, Kevin De Bruyne and Sergio Aguero also scored, with a Kevin Long own goal completing the demolition.
The win - City's eighth in succession since losing to Leicester on Boxing Day - comes three days after they reached Wembley in the League Cup and means Pep Guardiola's side, who trail leaders Liverpool by four points in the Premier League, are competing for trophies on four fronts.
"It is our eighth victory in a row and of course we have scored a lot of goals," Guardiola, who is seeking City's first FA Cup trophy since 2011, said.
"Everyone wants to help the team but there is always something to improve. Today they (Burnley) had one or two chances which we gave them."
Murray Wallace scored in stoppage time as Millwall came from behind to beat Everton 3-2 for their fifth straight home FA Cup win over a Premier League side.
Richarlison and Cenk Tosun twice put Everton ahead against Championship side Millwall, only for Lee Gregory and Jake Cooper to respond.
Cooper's goal controversially went in off his arm and set the stage for Wallace to slot home the winner in the 94th minute.
"The performance was brilliant, I thought we deserved something," Wallace told the BBC.
"I'm delighted to score the winner, I'm over the moon."
Watford beat fellow EPL club Newcastle 2-0 at St James' Park with goals from Andre Gray and Isaac Success.
Brighton & Hove Albion drew 0-0 at home with West Bromwich Albion, Doncaster Rovers defeated Oldham 2-1, Portsmouth drew 1-1 with Championship outfit Queens Park Rangers while Swansea City beat Gillingham 4-1.