Arab foreign ministers have told Syria to work to end months of bloodshed before it's too late, and will send the League's Secretary-General Nabil al-Arabi to Damascus to push for political and economic reforms.
But in a conciliatory message to Damascus, the ministers also said after an extraordinary meeting in Cairo that Syria's stability was crucial for the Arab World and the whole region.
The Syrian government has sent in troops and tanks to crush five months of street protests demanding President Bashar al-Assad steps down.
The UN says at least 2200 people have been killed since protests against the Syrian President began in March.
Syria says it is working hard to introduce reforms but blames militants for the violence.
It was the first official Arab League meeting on Syria since the start of the uprising.
The League, which groups the Arab world's 23 states, has been under pressure to speak out more openly following popular uprisings that ousted Arab heads of state in Tunisia and Egypt and led to the overthrow of Muammar Gaddafi in Libya.