English rugby Premiership leaders Harlequins have lost their unbeaten league record this season when champions Saracens beat them 19-11 in front of a record crowd at Twickenham.
The match between the Premiership's top two teams sold around 82,000 tickets in advance, ensuring a world record attendance for a regular season league match.
Harlequins had started the campaign with 10 successive wins but a try by England international David Strettle and four penalties by Owen Farrell sealed victory for Saracens.
Saracens have closed the gap at the top to five points.